We recommend you clear the SharePoint cache.
If you are unfamiliar with this process then this script might help you. https://gallery.technet.microsoft.com/office/Clear-Configuration-Cache-d55bcba9
To access the cache on the SharePoint server you may also come across a problem where you cannot access c:\ProgramData\ApplicationData This is likely because of security and this is again a known issue to us. Even as administrator you prompted with "Access denied".
The solution is to take ownership of the ApplicationData folder.